Semaglutide is an artificial medicinal product classified as a GLP-1 drug. It anaesthetises GLP-1, an important hormone for the human body. GLP-1 that is released from the gut plays an active role in blood glucose homeostasis and enhancement of insulin secretion. Furthermore, because of how Semaglutide works, it seems that this drug is not only effective for the treatment of diabetes and weight loss, but may also potentially be cardioprotective, hepatoprotective and organoprotective.

1.The working principle of Semaglutide

Semaglutide’s effect is similar to that of the GLP-1 hormone that serves to enhance multiple health outcomes through GLP-1 stimulating action. It comprises:

Insulin secretion enhancement: Semaglutide assists in influencing the pancreas regarding the generation of insulin and subsequently decreasing the amount of sugar in the blood. This effect grows stronger, especially after meals when the concentration of glucose in the blood is higher.

Putting a cap on the creation of glucose: This role serves to help in minimising the levels of glucose in the blood by means of preventing the generation of glucose within the liver - that is their action.

The delayed gastric emptying and decreased appetite stimulation: In addition, semaglutide slows down the rate of gastric emptying and decreases intestinal activity, which extends the duration of satiation, resulting in significantly decreased food intake and therefore weight loss.

Maintaining the health of the heart and the liver:  It appears that there is some evidence that suggests that Semaglutide could promote healthier livers and better heart function aids thus it could contribute positive changes to cardiovascular health.

2. Semaglutide application in diabetic management

As a GLP-1 receptor agonist, semaglutide is of utmost importance to those suffering from type 2 diabetes because it improves insulin output from the pancreas and lowers glucose synthesis by the liver. Semaglutide is one of the most recommended medications for type 2 diabetes management because it promotes weight loss while improving insulin sensitivity even if its blood-sugar-regulating capabilities are not fully utilised.

3. Milestones in weight loss with Semaglutide

Semaglutide is making rounds in the weight management community as their prominent clinical trials have proven that Semaglutide aids patients in great weight loss of more than 15 percent even after just 16 weeks. Its cool how people can beat targets while enjoying food. For these patients Semaglutide has proved to aid in the control of food intake by decreasing the appetite due to Semaglutide increasing gastric emptying.

4. Other areas of health Semaglutide can help with

As mentioned, Semaglutide can help with diabetes management, weight loss and further it has weighty benefits for other areas of health:

Cardiovascular Health: Semaglutide has been shown to improve blood sugar levels and even have an effect of reducing risk of cardiovascular complications. To diabetes patients, it can be heart protective and stroke preventative.

Liver Function: There is indication Semaglutide can be effective in managing fatty liver disease and other hepatic metabolic disorders.

5. Semaglutide potential positive side effects and negative side effects

Semaglutide has been shown to improve diabetes and weight loss but however there are some negative side effects. Among the frequent side effects include:

Nausea and vomiting: These are quite common side effects of Semaglutide, in some patients its always present especially during the first se of drugs.

Discomfort in the stomach: Symptoms include abdominal pains, diarrhoea, or constipation.

Low blood sugar concentration: Risk for low blood sugar increases if taken together with other medications to control blood glucose concentration.

Patients planning to use Semaglutide are advised to first consult their medical doctor ordering for it to determine if it is appropriate for their medical condition.

If you are to use the Semaglutide consult your medical doctor to make sure it is suitable for you considering other health factors including the treatment objectives.