Aromasin (Exemestane) is one of the recommendations given for an Aromatase Inhibitor treatment. It is usually indicated for patients suffering from oestrogen positive (ER positive) breast cancer. It is sold by various suppliers and manufacturers like TOP Peptide who are known as reputable suppliers for quality pharmaceutical products and chemicals. This article will discuss the uses, benefits, dosages, side effects, and the importance of Aromasin in the treatment of breast cancer.

What is Aromasin?

Aromasin is a drug in the class of Aromatase inhibitors (AIs) used to reduce estrogen levels, primarily in postmenopausal women.Estrogen is known to accelerate the growth of certain cancerous breast tissues, particularly ER-positive breast cancers. Aromasin achieves this by blocking the aromatase enzyme, which normally converts androgens into estrogen. The resulting decrease in oestrogen from By lowering estrogen levels, Aromasin prevents the multiplication of cancerous tissues that rely on estrogen for growth.

Aromasin is produced by several manufacturers including TOP Peptide. Aromasin is crucial for a breast cancer patient suffering from oestrogen involvement for treatment of breast cancer post surgery. It is commonly prescribed in the post-surgery and radiotherapy setting after an early stage breast cancer. It may also be used for advanced and metastatic breast cancer.

How Does Aromasin Work?

Aromasin’s main role is to inhibit the enzyme aromatase, the one responsible for the transformation of androgens (hormones synthesized by the adrenal glands) to oestrogen. Since oestrogen can accelerate the growth of certain forms of breast cancer, particularly the ER-positive ones, minimising the production of oestrogen is quite crucial to curb the growth of cancerous cells. Aromasin works in women who are postmenopausal, where aromatase is the primary source of oestrogen production and not the ovaries.

By lowering the levels of oestrogen, Aromasin works to prevent the recurrence of cancer in women who have previously been treated surgically and non-surgically for early breast cancer. It is also useful in the treatment of metastatic or advanced breast cancer, where the disease has spread to other regions of the body.

Aromasin Benefits

Aromasin provides additional benefits in the treatment of breast cancer, particularly for patients suffering from oestrogen receptor-positive (ER-positive) breast cancer:

Less Chances of Recurrence: After surgery for early-stage breast cancer, Aromasin is one of the remaining medications the patients will take. It works by greatly lowering oestrogen levels, thus preventing the return of cancer.

Effective in Advanced Cancer: Aromasin is useful in metastatic breast cancer. It helps control the speed at which the disease progresses. For this reason, it serves as a means of long-term control of advanced cancer.

Lower Oestrogen Related Effects: Aromasin is less likely to cause side effects defaulted to oestrogen such as hot flashes, mood changes, and dryness during and after the treatment hence improving the quality of life of the patient while receiving treatment for their condition.

Oestrogen related side effects are highly observable with most treatment options, but Aromasin has showed less frequency of related side effects.

Aromasin dosage

Aromasin is given after meals and a common starting dosage is 25mg per day. For patients that have earlier stages of breast cancer, Aromasin is usually prescribed for 5 years after a period of Tamoxifen treatment. Metastatic breast cancer is treated long term with Aromasin provided the patient has a positive reaction to the treatment throughout the duration. Their stage and predicted timeline for treatment will determine dosage, time period of treatment, and how the patient is progressing through treatment plans.

Make sure you follow the instruction given to you by your medical provider. Depending on each individual, the amount of medicine required will differ, therefore dosage and timing are critical towards optimal treatment outcome. Missed doses should only be taken if it is not too close to the next dose time.

Aromasin Side Effects

While Aromasin is a highly effective treatment, it may cause side effects in some patients. The most common side effects include:

Hot flashes: Many patients experience hot flashes that tend to be gradual and mild due to oestrogen suppression.

Joint pain: Some patients experience musculoskeletal discomfort that manifests as painful joints, stiff limbs, or both.

Fatigue: People taking Aromasin generally feel more tired or sluggish than normal, which may interfere with day-to-day tasks.

Night sweats: Increased perspiration, especially at night, is another common complaint.

Headaches: Some people may suffer from headaches because of the fluctuations in hormones.

These are side effects that are categorised as serious, and while they are not very common, some patients could also experience:

Bone thinning: Aromasin might lower the patient's bone mineral density, increasing their chances of fractures. Therefore, monitoring bone density is advised during treatment.

Heart issues: Particularly in already afflicted individuals, Aromasin might induce heart problems like heart failure.

Liver function: In very uncommon situations, Aromasin might alter liver functionality. Regular monitoring is important for those who are at risk.

Important Considerations

Women who are premenopausal females are not recommended for Aromasin: Women who are still producing oestrogen due to their ovaries are not recommended for Aromasin. The medication works best in postmenopausal women, where aromatase carries out most of oestrogen synthesis.

Drug interactions: Aromasin has the potential to interact with other drugs, which makes it necessary for patients to discuss all medications, vitamins, and supplements they take with their healthcare provider.

Pregnancy and breast feeding: Women who are pregnant or nursing should not use Aromasin, as it can be harmful while in these stages.

Bone health: As Aromasin has the effect of bone thinning, regular check-ups on bone health are recommended, with the possibility of using calcium and vitamin D supplements.

Aromasin has proven to be one of the strongest medications aimed at treating breast cancer in women with a positive oestrogen receptor, especially older women who are already in their menopausal phase. It prevents the growth and spread of cancer cells which are nourished by oestrogen by lowering the oestrogen levels. Aromasin is manufactured by reputable companies, including TOP Peptide, which offers a dependable solution for patients looking to control their breast cancer over the years.

This medication may result in side effects; however, some patients experience that the benefits are much more significant than the risks. Do not forget to speak to a doctor regarding the course of treatment with Aromasin. After careful observation and following well-established dosage regimes, Aromasin will help many patients suffering from ER positive breast cancer.